Toll-like receptor 4 polymorphisms and idiopathic chromosomally normal miscarriage
نویسندگان
چکیده
منابع مشابه
Toll-like receptor 4 polymorphisms and idiopathic chromosomally normal miscarriage.
BACKGROUND Lipopolysaccharide (LPS or endotoxin) exposure resulting from microbial invasion of the endometrium disturbs the Th1/Th2 balance at the feto-maternal interface and has been linked to the risk of idiopathic miscarriage in a range of human and animal studies. Toll-like receptor 4 (TLR4) mediates LPS signalling, and the human TLR4 gene harbours two single-nucleotide polymorphisms (SNPs)...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2006
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/del377